![]() Ultrasound Med Biol 32:1753–1761Ĭlement GT, Hynynen K (2002a) Micro-receiver guided transcranial beam steering. IEEE Trans Ultrason Ferroelectr Freq Control 59:150–155Ĭivale J, Clarke RL, Rivens IH, ter Haar GR (2006) The use of a segmented transducer for rib sparing in HIFU treatments. Curr Opin Orthop 16:494–500Ĭhen GS, Lin CY, Jeong JS, Cannata JM, Lin WL, Chang H, Shung KK (2012) Design and characterization of dual-curvature 1.5-dimensional high-intensity focused ultrasound phased-array transducer. Ultrasound Med Biol 29:725–737Ĭhen W, Zhou K (2005) High-intensity focused ultrasound ablation: a new strategy to manage primary bone tumors. Zhonghua Zhong Liu Za Zhi 24:612–615Ĭhen WS, Brayman AA, Matula TJ, Crum LA (2003) Inertial cavitation dose and hemolysis produced in vitro with or without Optison®. J Endourol 15:437–440Ĭhen W, Wang Z, Wu F, Zhu H, Zou J, Bai J, Li K, Xie F (2002) High intensity focused ultrasound in the treatment of primary malignant bone tumor. Ultrasound Med Biol 26:153–159Ĭhaussy C, Thuroff S, de la Rosette JJMC (2001) Results and side effects of high-intensity focused ultrasound in localized prostate cancer. Med Phys 29:2611–2620Ĭhapelon JY, Cathignol D, Cain C, Ebbini E, Kluiwstra JU, Sapozhnikov OA, Guey JL (2000) New piezoelectric transducers for therapeutic ultrasound. IEEE Trans Biomed Eng 60:2751–2759Ĭhan AH, Fujimoto VY, Moore DE, Martin RW, Vaezy S (2002) An image-guided high intensity focused ultrasound device for uterine fibroids treatment. J Neurosurg 17:858–876Ĭasper AJ, Liu D, Ballard JR, Ebbini ES (2013) Real-time implementation of a dual-mode ultrasound array system: in vivo results. J Acoust Soc Am 129:2677–2677īallantine HT, Bell E, Manlapaz J (1960) Progress and problems in the neurological application of focused ultrasound. ![]() IEEE Trans Sonics Ultrasonics 29:18–25īailey MR, Maxwell AD, Pishchalnikov YA, Sapozhnikov OA (2011) Polyvinylidene fluoride membrane hydrophone low‐frequency response to medical shockwaves. BJU Int 114:532–540īacon DR (1982) Characteristics of a PVDF membrane hydrophone for use in the range 1–100 MHz. J Acoust Soc Am 113:84–93īaco E, Gelet A, Crouzet S, Rud E, Rouvière O, Tonoli‐Catez H, Eggesbø HB (2014) Hemi salvage high‐intensity focused ultrasound (HIFU) in unilateral radiorecurrent prostate cancer: a prospective two‐centre study. Phys Med Biol 53:2937–2951Īubry JF, Tanter M, Pernot M, Thomas JL, Fink M (2003) Experimental demonstration of noninvasive trans-skull adaptive focusing based on prior computed tomography scans. Curr Med Res Opin 30:1599–1605Īubry JF, Pernot M, Marquet F, Tanter M, Fink M (2008) Transcostal high-intensity-focused ultrasound: ex vivo adaptive focusing feasibility study. Investig Ophthalmol Vis Sci 52:8747–8753Īptel F, Dupuy C, Rouland JF (2014) Treatment of refractory open-angle glaucoma using ultrasonic circular cyclocoagulation: a prospective case series. Cancer Treat Rev 38:346–353Īptel F, Charrel T, Lafon C, Romano F, Chapelon JY, Blumen-Ohana E, Denis P (2011) Miniaturized high-intensity focused ultrasound device in patients with glaucoma: a clinical pilot study. High Intensity Focused Ultrasound (HIFU)Īl-Bataineh O, Jenne J, Huber P (2012) Clinical and future applications of high intensity focused ultrasound in cancer. ![]() Their principle of operation is described here, and an overview of their design principles is given. Numerous extra-corporeal, transrectal and interstitial devices have been designed to optimize application-specific treatment delivery for the wide-ranging areas of application that are now being explored with HIFU. Sources placed either outside the body (for treatment of tumors or abnormalities of the liver, kidney, breast, uterus, pancreas brain and bone), or in the rectum (for treatment of the prostate), provide rapid heating of a target tissue volume, the highly focused nature of the field leaving tissue in the ultrasound propagation path relatively unaffected. HIFU scores over other thermal ablation techniques because of the lack of necessity for the transcutaneous insertion of probes into the target tissue. ![]() Usually requiring only a single session, treatments are often conducted as day case procedures, with the patient either fully conscious, lightly sedated or under light general anesthesia. High intensity focused ultrasound (HIFU) is rapidly gaining clinical acceptance as a technique capable of providing non-invasive heating and ablation for a wide range of applications. ![]()
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